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Musculoskeletal cytohistology

by Lester J. Layfield

"Each volume in this richly illustrated series, sponsored by the Papanicolaou Society of Cytopathology, provides an organ-based approach to the cytological and histological diagnosis of small tissue samples. Benign, pre-malignant and malignant entities are presented in a well-organized and standardized format, with high-resolution color photomicrographs, tables, tabulated specific morphologic criteria and appropriate ancillary testing algorithms. Example vignettes allow the reader to assimilate the diagnostic principles in a case-based format. This volume describes the cytologic, small core biopsy, immunohistochemical and molecular diagnostic features of musculoskeletal lesions. It provides the cytopathologist and histopathologist with a comprehensive survey of diagnostic approaches and diagnostic features for benign and malignant lesions. Each chapter contains a detailed summary of differential diagnostic features, supported by high-quality images and case studies. With over 500 printed photomicrographs and a CD-ROM offering all images in a downloadable format, this is an important resource for practising pathologists and residents in pathology"--Provided by publisher. "Principles and Practice for Biopsy Diagnosis and Management of Musculoskeletal Lesions Introduction to the Diagnosis of Musculoskeletal Lesions Fine-needle aspiration and core biopsy are used at some oncology centers as the initial technique to obtain a tissue diagnosis for mass lesions occurring within the musculoskeletal system. A majority of such lesions are in actuality metastatic deposits from a primary malignancy arising elsewhere. Metastatic neoplasms usually present little difficulty in diagnosis. Primary lesions of the musculoskeletal system are a significantly greater diagnostic challenge and many authorities in histopathology of bone and soft tissue tumors have recommended against the use of small biopsy techniques for the diagnosis of these lesions. The resistance to the use of small volume specimens, especially fine-needle aspiration (FNA), results from a combination of factors including the relative rarity of these lesions, the potential for radical deforming surgery and the young age of the patients in which many of these lesions occur. Musculoskeletal sarcomas account for less than one percent of all malignant neoplasms. "--Provided by publisher.